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During her time as a resident, Grey works alongside fellow doctors Cristina Yang (Sandra Oh), Izzie Stevens (Katherine Heigl), Alex Karev (Justin Chambers), and George O'Malley (T. Knight), who each struggle to balance personal lives with the hectic work and training schedules.
They are overseen during their internship by Miranda Bailey (Chandra Wilson), a senior resident who works for attending Derek Shepherd (Patrick Dempsey), the head of neurosurgery and Meredith's love interest; Preston Burke (Isaiah Washington), the head of cardio, who becomes Yang's fiancé; and Richard Webber (James Pickens, Jr.), the Chief of Surgery and attending general surgeon, and lover of Ellis Grey decades before.
While its ratings have fallen over the course of its run (it was once among the overall top 10 shows in the United States), it is still one of the highest-rated shows among the 18–49 demographic, and the No. Grey's Anatomy has been well received by critics throughout much of its run, and has been included in various critics' year-end top ten lists.
Since its inception, the show has been described by the media outlets as a television "phenomenon" or a "juggernaut", owing to its longevity and dominant ratings.
: I've been lying in this bed for close to a year, and I've had a lot of time to look back on my life.
Meredith is devastated by the latest blow to her love life.
Grey's Anatomy is an American medical drama television series that premiered on March 27, 2005, on American Broadcasting Company (ABC) as a mid-season replacement.
The fictional series focuses on the lives of surgical interns, residents, and attending physicians, as they develop into seasoned doctors while trying to maintain personal lives and relationships.
The cast has undergone major changes through the series' run, with many members leaving and being replaced by others.
In its twelfth season, the show had a large ensemble of sixteen actors, including four characters from the original cast (Meredith Grey, Alex Karev, Miranda Bailey, and Richard Webber).
On February 10, 2017, ABC renewed Grey's Anatomy for a fourteenth season, which premiered on September 28, 2017.